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Moleküler Biyoloji ve Biyokimya Ürünleri
Merck 102584 Caffeine EMPROVE® ESSENTIAL Ph Eur, BP, USP 50 kg

Merck 102584 Caffeine EMPROVE® ESSENTIAL Ph Eur, BP, USP 50 kg

Merck 102584 Caffeine EMPROVE® ESSENTIAL Ph Eur, BP, USP 50 kg

Kategori

Moleküler Biyoloji ve Biyokimya Ürünleri , Diğer Analitik Kimyasallar

Marka

MERCK

Stok Kodu

LB.M.102584.9050

Sepete Ekle

Teklif Sepetine Ekle

Merck 102584 Caffeine EMPROVE® ESSENTIAL Ph Eur, BP, USP 50 kg
Catalogue Number	102584
Synonyms	7-Methyltheobromine, 1,3,7-Trimethylxanthine, 3,7-Dihydro-1,3,7-trimethyl-1H-purine-2,6-dione

Merck 102584 Caffeine EMPROVE® ESSENTIAL Ph Eur, BP, USP

Product Information
CAS number	58-08-2
EC index number	613-086-00-5
EC number	200-362-1
Grade	Ph Eur,BP,USP
Hill Formula	C₈H₁₀N₄O₂
Molar Mass	194.19 g/mol
HS Code	2939 30 00
Structure formula Image
Quality Level	MQ500

Physicochemical Information
Density	1.23 g/cm3 (18 °C)
Ignition temperature	>600 °C
Melting Point	235 - 239 °C
pH value	5.5 - 6.5 (10 g/l, H₂O, 20 °C)
Vapor pressure	20 hPa (80 °C)
Bulk density	220 kg/m3
Solubility	20 g/l

Toxicological Information
LD 50 oral	LD50 Rat 367.7 mg/kg

Safety Information according to GHS
Hazard Pictogram(s)
Hazard Statement(s)	H302: Harmful if swallowed.
Precautionary Statement(s)	P264: Wash skin thoroughly after handling. P270: Do not eat, drink or smoke when using this product. P301 + P312: IF SWALLOWED: Call a POISON CENTER/doctor if you feel unwell. P501: Dispose of contents/ container to an approved waste disposal plant.
Signal Word	Warning
Storage class	10 - 13 Other liquids and solids
WGK	WGK 1 slightly hazardous to water
Disposal	3 Relatively unreactive organic reagents should be collected in container A. If halogenated, they should be collected in container B. For solid residues use container C.

Safety Information
Categories of danger	harmful

Storage and Shipping Information
Storage	Store at +2°C to +30 °C.

Transport Information
Declaration (railroad and road) ADR, RID	Kein Gefahrgut
Declaration (transport by air) IATA-DGR	No Dangerous Good
Declaration (transport by sea) IMDG-Code	No Dangerous Good

Specifications
Assay (perchloric acid titration, calculated on dried substance)	98.5 - 101.5 %
Assay (HPLC, calc. on anhydrous substance)	98.5 - 101.0 %
Identity (IR)	passes test
Identity (HPLC)	passes test
Identity (wet chemistry)	passes test
Identity (Melting point)	234 - 239 °C
Appearance of solution (1 %; water)	passes test
Acidity	passes test
Sulfate (SO₄)	≤ 500 ppm
Chloroform (HS-GC)	≤ 60 ppm
Related substances (HPLC, EP) (Highest single impurity)	≤ 0.10 %
Related substances (HPLC, EP) (Sum of all impurities)	≤ 0.10 %
Chromatographic purity (USP) (Highest single impurity)	≤ 0.1 %
Chromatographic purity (USP) (Sum of all impurities)	≤ 0.1 %
Theophylline (HPLC)	≤ 0.10 %
Other residual solvents (ICH Q3C)	excluded by the manufacturing process
Sulfated ash	≤ 0.1 %
Loss on Drying (105 °C)	≤ 0.5 %
Elemental impurity specifications have been set considering ICH Q3D (Guideline for Elemental Impurities). Class 1-3 elements are not likely to be present above the ICH Q3D option 1 limit, unless specified and indicated (*).
Corresponds to Ph Eur, BP, USP

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