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Merck 106756 Methyl 4-hydroxybenzoate sodium salt EMPROVE® ESSENTIAL Ph Eur, BP, NF 20 kg

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Stok Kodu
LB.M.1067569024
Merck 106756 Methyl 4-hydroxybenzoate sodium salt EMPROVE® ESSENTIAL Ph Eur, BP, NF 20 kg
Catalogue Number 106756
Synonyms 4-Hydroxybenzoic acid methyl ester sodium salt, Methylparaben sodium salt
Description Methyl 4-hydroxybenzoate sodium salt
Merck 106756 Methyl 4-hydroxybenzoate sodium salt EMPROVE® ESSENTIAL Ph Eur, BP, NF 
 
Product Information
CAS number 5026-62-0
EC number 225-714-1
Grade Ph Eur,BP,NF
Hill Formula C₈H₇NaO₃
Chemical formula Na⁺[4-(O)C₆H₄(COOCH₃)]⁻
Molar Mass 174.13 g/mol
HS Code 2918 29 00
Structure formula Image Structure formula Image
Quality Level MQ500
Physicochemical Information
Density 1.42 g/cm3 (20 °C)
Ignition temperature >600 °C
Melting Point >125 °C
pH value 9.7 - 10.3 (1 g/l, H₂O)
Bulk density 700 kg/m3
Solubility 333 g/l
Toxicological Information
LD 50 oral LD50 Rat > 5000 mg/kg
Safety Information according to GHS
Hazard Pictogram(s) Hazard Pictogram(s)
Hazard Statement(s) H315: Causes skin irritation.
H318: Causes serious eye damage.
H412: Harmful to aquatic life with long lasting effects.
Precautionary Statement(s) P264: Wash skin thoroughly after handling.
P273: Avoid release to the environment.
P280: Wear protective gloves/ eye protection/ face protection.
P302 + P352: IF ON SKIN: Wash with plenty of water.
P305 + P351 + P338: IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
P332 + P313: If skin irritation occurs: Get medical advice/ attention.
Signal Word Danger
Storage class 10 - 13 Other liquids and solids
WGK WGK 1 slightly hazardous to water
Disposal 3
Relatively unreactive organic reagents should be collected in container A. If halogenated, they should be collected in container B. For solid residues use container C.
Safety Information
Categories of danger irritant
Storage and Shipping Information
Storage Store at +15 °C to +25 °C.
Transport Information
Declaration (railroad and road) ADR, RID Kein Gefahrgut
Declaration (transport by air) IATA-DGR No Dangerous Good
Declaration (transport by sea) IMDG-Code No Dangerous Good
Specifications
Assay (HPLC, calc. on anhydrous substance, Ph.Eur.) 95.0 - 102.0 %
Assay (HPLC, calc. on anhydrous substance, NF) 95.0 - 102.0 %
Identity (IR-spectrum) passes test
Identity (wet chemistry) passes test
Appearance of solution (100 g/l, CO₂-free water) clear and not more intense in color than reference solution BY₆
Solubility passes test
pH-value (1 g/l in CO₂-free Water) 9.5 - 10.5
Chloride (Cl) ≤ 350 ppm
Sulfate (SO₄) ≤ 300 ppm
Related substances (HPLC, Ph. Eur.) passes test
4-Hydroxy benzoic acid (Ph. Eur.) ≤ 3.0 %
Sum of all impurities (without 4-Hydroxybenzoic acid (Ph.Eur.)) ≤ 1.0 %
Largest unspecified impurity (Ph.Eur.) ≤ 0.5 %
Related substances (HPLC, NF) passes test
4-Hydroxy benzoic acid (NF) ≤ 3.0 %
Sum of all impurities (without 4-Hydroxybenzoic acid (NF)) ≤ 1.0 %
Largest unspecified impurity (NF) ≤ 0.5 %
Methanol (HS-GC) ≤ 3000 ppm
Other residual solvents (ICH Q3C) excluded by manufactoring process
Water (according to Karl Fischer) ≤ 5.0 %
Elemental impurity specifications have been set considering ICH Q3D (Guideline for Elemental Impurities). Class 1-3 elements are not likely to be present above the ICH Q3D option 1 limit, unless specified and indicated (*).
Corresponds Ph Eur, BP,NF
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Merck 106756 Methyl 4-hydroxybenzoate sodium salt EMPROVE® ESSENTIAL Ph Eur, BP, NF 20 kg Merck 106756 Methyl 4-hydroxybenzoate sodium salt EMPROVE® ESSENTIAL Ph Eur, BP, NF 20 kg LB.M.1067569024
Merck 106756 Methyl 4-hydroxybenzoate sodium salt EMPROVE® ESSENTIAL Ph Eur, BP, NF 20 kg

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