Sigma-Aldrich 341006 EDAC, Hydrochloride 25 gr
Marka
Stok Kodu
LB.SA.341006-25GM
Kısa Bilgi
Synonym(s): EDAC, Hydrochloride, EDCI, 1-Ethyl-3-(3ʹ-dimethylaminopropyl)carbodiimide, HCl Empirical Formula (Hill Notation): C8H17N3 · xHCl CAS Number: 25952-53-8 Molecular Weight: 155.24 (free base basis) MDL number: MFCD00012503 UNSPSC Code: 41116133 NACRES: NA.21
Bilgi
CAS Number: 25952-53-8
| Sigma-Aldrich 341006 EDAC, Hydrochloride 25 gr |
| EDAC HCl is a water-soluble derivative of carbodiimide useful for conjugating haptens to proteins and polypeptides. Used to modify NMDA receptors and as a condensing agent in peptide synthesis. Synonym(s): EDAC, Hydrochloride, EDCI, 1-Ethyl-3-(3ʹ-dimethylaminopropyl)carbodiimide, HCl Empirical Formula (Hill Notation): C8H17N3 · xHCl CAS Number: 25952-53-8 Molecular Weight: 155.24 (free base basis) MDL number: MFCD00012503 UNSPSC Code: 41116133 NACRES: NA.21 |
| PROPERTIES Quality Level 200 Assay ≥98% (titration) form solid manufacturer/tradename Calbiochem® storage condition OK to freeze desiccated color white solubility aqueous buffer: 2-5 mg/mL water: 2-5 mg/mL shipped in ambient storage temp. −20°C InChI 1S/C8H17N3.ClH/c1-4-11(8-9)7-5-6-10(2)3;/h4-7H2,1-3H3;1H InChI key FDXPUDRRFDHONO-UHFFFAOYSA-N DESCRIPTION General description Molar absorptivity (~212 nm; 50 mM phosphate buffer, pH 8):≥6800 M-1cm-1. Water-soluble carbodiimide derivative. Used to modify NMDA receptors. Also useful for conjugating haptens to proteins or polypeptides. Water-soluble derivative of carbodiimide useful for conjugating haptens to proteins and polypeptides. Used to modify NMDA receptors and as a condensing agent in peptide synthesis. The major advantage of EDAC coupling is the easy removal of excess reagent and the corresponding urea by washing with dilute acid or water. Carbodiimides catalyze the formation of amide bonds, carboxylic acids, and amines by activating the carboxylate to form an O-acylurea. This intermediate can be attacked by an amine directly to form an amide. EDAC is released as a soluble urea derivative. Packaging Packaged under inert gas Warning Toxicity: Irritant (B) Preparation Note Avoid amine containing buffers. Reconstitution Unstable in solution. Reconstitute just prior to use. Other Notes Chazot, P.L., et al. 1993. Biochem. Pharmacol. 45, 605. Richardson, A., et al. 1992. Biochem. Pharmacol. 43, 1415. Taniuchi, M., et al. 1986. Proc. Natl. Acad. Sci. USA83, 1950. Chase, J.W., et al. 1983. Proc. Natl. Acad. Sci. USA80, 5480. Williams, A., et al. 1981. J. Am. Chem. Soc.103, 7090. Yamada, H., et al. 1981. Biochemistry20, 4836. Thomas, J.O., et al. 1978. J. Mol. Biol.123, 149. Ozawa, H. 1970. Biochemistry9, 2158. Kopple, K.D., et al. 1962. J. Am. Chem. Soc.84, 4457. Legal Information CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany |
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