Sigma-Aldrich 408719 Polyethylenimine, branched average Mw ~800 by LS, average Mn ~600 by GPC 1 L
Kategori
Marka
Stok Kodu
LB.SA.408719-1L
Kısa Bilgi
Synonym(s): PEI, ethylenediamine branched Linear Formula: H(NHCH2CH2)nNH2 CAS Number: 25987-06-8 MDL number: MFCD00084427 NACRES: NA.23
Sigma-Aldrich 408719 Polyethylenimine, branched average Mw ~800 by LS, average Mn ~600 by GPC |
Synonym(s): PEI, ethylenediamine branched
Linear Formula: H(NHCH2CH2)nNH2
CAS Number: 25987-06-8
MDL number: MFCD00084427
NACRES: NA.23
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PROPERTIES
form viscous liquid
Quality Level 200
mol wt
average Mn ~600 by GPC
average Mw ~800 by LS
refractive index n20/D 1.5240
density 1.050 g/mL at 25 °C
InChI 1S/C2H8N2.C2H5N/c3-1-2-4;1-2-3-1/h1-4H2;3H,1-2H2
InChI key SFLOAOINZSFFAE-UHFFFAOYSA-N
DESCRIPTION
General description
Polyethyleneimine is a hydrophilic polymerwidely used as a non-viral synthetic vector for invivo delivery of therapeutic nucleic acids. Owing to its excellentphysicochemical properties, it is applied in many fields like the separationand purification of proteins, carbon dioxide absorption, drug carriers,effluent treatment, and biological labels.
Application
Branched PEI can be used as a precursor to synthesize conjugated polyplexes for efficient gene transfection. Conjugation of PEI with Jeffamine polyether and guanidinylation of the amino groups of PEI reduce the cytotoxicity of the polyplexes and protect them from aggregation in the presence of serum proteins.
Bamboo charcoal impregnated with PEI can be used as a CO2 adsorbent. Numerous amino groups present in PEI can react with CO2 due to acid-alkali interaction and enhance the adsorption capacity of bamboo charcoal.
It can also be used to prepare cross-linked water-soluble polymers with high coordination capabilities towards organic drug molecules.
Packaging
100, 250 mL in glass bottle
1 L in glass bottle
Features and Benefits
Branched PEI has better complexation and buffering capacity.
High ion exchange capacity and affinity toward proteins.
SignificantDNA transfer efficiency.
Physical form
Branched polymer
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