Sigma-Aldrich 43816 DL-Dithiothreitol solution BioUltra, for molecular biology, ~1 M in H2O 10 mL
Marka
Stok Kodu
LB.SA.43816-10ML
Kısa Bilgi
Synonym(s): (±)-threo-1,4-Dimercapto-2,3-butanediol solution, DTT Empirical Formula (Hill Notation): C4H10O2S2 CAS Number: 3483-12-3 Molecular Weight: 154.25 Beilstein: 1719757 MDL number: MFCD00004877 PubChem Substance ID: 57650196 NACRES: NA.25
| Sigma-Aldrich 43816 DL-Dithiothreitol solution BioUltra, ~1 M in H2O 10 mL |
|
Synonym(s): (±)-threo-1,4-Dimercapto-2,3-butanediol solution, DTT
Empirical Formula (Hill Notation): C4H10O2S2
CAS Number: 3483-12-3
Molecular Weight: 154.25
Beilstein: 1719757
MDL number: MFCD00004877
PubChem Substance ID: 57650196
NACRES: NA.25 |
|
PROPERTIES
grade for molecular biology
Quality Level 200
product line BioUltra
form liquid
concentration ~1 M in H2O
impurities
DNases, none detected
RNases, none detected
phosphatases, none detected
proteases, none detected
pH 2.7-5.0
density 1.04 g/mL at 20 °C
absorption cut-off at 330 nm
suitability in accordance for filter test
storage temp. 2-8°C
SMILES string O[C@H](CS)[C@H](O)CS
InChI 1S/C4H10O2S2/c5-3(1-7)4(6)2-8/h3-8H,1-2H2/t3-,4-/m1/s1
InChI key VHJLVAABSRFDPM-QWWZWVQMSA-N
DESCRIPTION
Application
DL-dithiothreitol solution has been used:
in the treatment of intestinal explants[1]
in homogenate preparation of gill cells for enzymatic assays[2]
in western blotting[3]
in transglutaminase activity[4]
Packaging
10, 50, 250 mL
Biochem/physiol Actions
DL-dithiothreitol (DTT) is used in a chemical debonding technique, that helps to remove bacteria from biofilms.[5] It can change the structural stability of the GABA(B) (gamma-aminobutyric acid) receptor by disabling the disulfide bonds between four cysteine residues positioned in the GABA(B1(a)) receptor structure.[6] |
