Sigma Aldrich 730114 2-Methacryloyloxyethyl phosphorylcholine contains ≤100 ppm MEHQ as inhibitor, 97% 5 gr
Kategori
Marka
Stok Kodu
LB.SA.730114-5G
Kısa Bilgi
Synonym(s): MPC Empirical Formula (Hill Notation): C11H22NO6P CAS Number: 67881-98-5 Molecular Weight: 295.27 MDL number: MFCD11112180 PubChem Substance ID: 329764541 NACRES: NA.23
| Sigma Aldrich 730114 2-Methacryloyloxyethyl phosphorylcholine |
|
Synonym(s): MPC
Empirical Formula (Hill Notation): C11H22NO6P
CAS Number: 67881-98-5
Molecular Weight: 295.27
MDL number: MFCD11112180
PubChem Substance ID: 329764541
NACRES: NA.23 |
|
PROPERTIES
Quality Level 100
Assay 97%
form liquid
contains ≤100 ppm MEHQ as inhibitor
mp 143-148 °C
storage temp. 2-8°C
SMILES string CC(=C)C(=O)OCCOP([O-])(=O)OCC[N+](C)(C)C
InChI 1S/C11H22NO6P/c1-10(2)11(13)16-8-9-18-19(14,15)17-7-6-12(3,4)5/h1,6-9H2,2-5H3
InChI key ZSZRUEAFVQITHH-UHFFFAOYSA-N
DESCRIPTION
General description
Methacryloyloxyethyl phosphorylcholine (MPC), containing a phosphorylcholine group in the side chain is a most suitable monomer to mimic the phospholipid polar groups contained with cell membranes. MPC block copolymers are biocompatible in nature; it shows desirable interaction with living tissues. It is hydroscopic in nature.
Application
2-Methacryloyloxyethyl phosphorylcholine (MPC) can be used as a monomer in the preparation of polymer grafted Fe3O4 nanoparticles via the atom transfer radical polymerization (ATRP) method.
It can be used to prepare CRP inhibitors and biosensors as it can specifically recognize C-reactive protein. It can also be used to prepare polymer-modified antifouling silicone hydrogel contact lenses.
The addition of MPC forms a cell membrane-like structure on the contact lens and helps to prevent cell and bacterial adhesion on the surface.
Features and Benefits
- It has bioinert properties due to the presence of a zwitter ionic phosphorylcholine (PC) group in the side chain.
- It can build various molecular architectures with tunable properties.
- It has excellent resistance to cell adhesion, blood coagulation, and non-specific protein adsorption. |
