Sigma-Aldrich A1653 Albumin from human serum lyophilized powder, ≥96% (agarose gel electrophoresis) CAS No.: 70024-90-7 10 gr
Marka
Stok Kodu
LB.SA.A1653-10G
Kısa Bilgi
Synonym(s): HSA CAS Number: 70024-90-7 EC Number: 274-272-6 MDL number: MFCD00081418 UNSPSC Code: 12352202 eCl@ss: 42010201 NACRES: NA.25
| Sigma-Aldrich A1653 Albumin from human CAS No.: 70024-90-7 |
| Synonym(s): HSA CAS Number: 70024-90-7 EC Number: 274-272-6 MDL number: MFCD00081418 UNSPSC Code: 12352202 eCl@ss: 42010201 NACRES: NA.25 |
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PROPERTIES
biological source human
Assay ≥96% (agarose gel electrophoresis) form lyophilized powder mol wt monomer calculated mol wt 66478 Da technique(s) ELISA: suitable tissue culture: suitable western blot: suitable impurities HIV I and HIVII, HCV and HBsAg, tested negative solubility H2O: soluble 50 mg/mL UniProt accession no. P02768 storage temp. 2-8°C SMILES string FC(F)(F)C(F)(F)C(F)(F)F InChI 1S/C3F8/c4-1(5,2(6,7)8)3(9,10)11 InChI key QYSGYZVSCZSLHT-UHFFFAOYSA-N Gene Information human ... ALB(213) DESCRIPTION General description Albumin (ALB) constitutes 25% of the proteins produced by the liver.[1] It is a protein of a single polypeptide chain with a thiol group.[2] The ALB gene is mapped to human 4q13.3.[3] Application Albumin from human serum has been used: - in cyclophilin isomerase assay[4] - as a component in blocking solution for immunogold quantification of amino acids and proteins in complex subcellular compartments[5] - in G-pseudotyped HIV (PHIV) assay mixture to study its effect on GSK364735 antiviral potency[6] Albumin was used to test its effect on the in vitro bactericidal activity of cefditoren against penicillin-resistant Streptococcus pneumonia.[7] It has been clinically used in serious and often life-threatening conditions, such as shock and blood loss due to trauma, burns, and surgery.[8] Biochem/physiol Actions Albumin serves as a protein repository and functions as a binding and transport protein. Albumin binding dissolves the biomolecules in blood and ensures its effective transport. This prevents the loss of substance through excretion.[9] Pathological conditions like vasculitis, lymphangiectasia, glomerulonephritis, and hepatic sinusoidal hypertension might result in hypoalbuminemia.[1] Albumins are soluble monomeric proteins found in the body fluids and tissues of animals and in some plant seeds. Serum albumin functions as a carrier protein for steroids, fatty acids, and thyroid hormones. Serum albumins are also vital in regulating the colloidal osmotic pressures of blood. Serum albumin functions as a carrier protein for steroids, fatty acids, and thyroid hormones, and is vital in regulating the colloidal osmotic pressures of blood. Albumin is also seen to bind to exogenous substances, particularly drugs (e.g., ibuprofen, warfarin), and strongly influence their pharmacokinetics. Oxidative stress leading to changes in the redox state of albumin has widely varied effects on its physiological function. Quality Remainder mostly globulins Other Notes View more information on human serum albumin. Disclaimer RESEARCH USE ONLY. This product is regulated in France when intended to be used for scientific purposes, including for import and export activities (Article L 1211-1 paragraph 2 of the Public Health Code). The purchaser (i.e. enduser) is required to obtain an import authorization from the France Ministry of Research referred in the Article L1245-5-1 II. of Public Health Code. By ordering this product, you are confirming that you have obtained the proper import authorization. |
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