Sigma-Aldrich B0125 Bacitracin from Bacillus licheniformis, ≥65 IU/mg 50000 UNITS
Marka
Stok Kodu
LB.SA.B0125-50KU
| Sigma-Aldrich B0125 Bacitracin from Bacillus licheniformis, ≥65 IU/mg 50000 UNITS |
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Empirical Formula (Hill Notation): C66H103N17O16S
CAS Number: 1405-87-4
Molecular Weight: 1422.69
EC Number: 215-786-2
MDL number: MFCD00062640
PubChem Substance ID: 24891503
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PROPERTIES
biological source Bacillus licheniformis
Quality Level 200
form powder
specific activity ≥65 IU/mg
antibiotic activity spectrum Gram-positive bacteria
Mode of action cell wall synthesis | interferes
storage temp. 2-8°C
SMILES string [H]N1[C@@H](Cc2cnc[nH]2)C(=O)N[C@H](CC(O)=O)C(=O)N[C@@H](CC(N)=O)C(=O)NCCCC[C@H](NC(=O)[C@@H](NC(=O)[C@@H](CCC(O)=O)NC(=O)[C@H](CC(C)C)NC(=O)C3CSC(=N3)C(N)C(C)CC)[C@@H](C)CC)C(=O)N[C@H](CCCN)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@H](Cc4ccccc4)C1=O
InChI 1S/C66H103N17O16S/c1-9-35(6)52(69)66-81-48(32-100-66)63(97)76-43(26-34(4)5)59(93)74-42(22-23-50(85)86)58(92)83-53(36(7)10-2)64(98)75-40-20-15-16-25-71-55(89)46(29-49(68)84)78-62(96)47(30-51(87)88)79-61(95)45(28-39-31-70-33-72-39)77-60(94)44(27-38-18-13-12-14-19-38)80-65(99)54(37(8)11-3)82-57(91)41(21-17-24-67)73-56(40)90/h12-14,18-19,31,33-37,40-48,52-54H,9-11,15-17,20-30,32,67,69H2,1-8H3,(H2,68,84)(H,70,72)(H,71,89)(H,73,90)(H,74,93)(H,75,98)(H,76,97)(H,77,94)(H,78,96)(H,79,95)(H,80,99)(H,82,91)(H,83,92)(H,85,86)(H,87,88)/t35?,36-,37-,40-,41+,42+,43-,44+,45-,46-,47+,48?,52?,53-,54-/m0/s1
InChI key CLKOFPXJLQSYAH-RNHDWVCBSA-N
DESCRIPTION
General description
Chemical structure: peptide
Application Bacitracin is used to study disruption of bacterial cell wall synthesis at the level of peptidoglycan cross-linking and isoprenyl metabolism.
Biochem/physiol Actions
Bacitracin is a peptide antibiotic. Antimicrobial spectrum: Gram-positive bacteria. Mode of Action: Inhibits bacterial cell wall synthesis by inhibiting dephosphorylation of lipid pyrophosphate.
Other Notes
Keep container tightly closed in a dry and well-ventilated place. |