Sigma-Aldrich BP227 Metformin hydochloride British Pharmacopoeia (BP) Reference Standard 100 mg
Kategori
Marka
Stok Kodu
LB.SA.BP227
Kısa Bilgi
Synonym(s): 1,1-Dimethylbiguanide hydrochloride, Metformin, Linear Formula: NH2C(=NH)NHC(=NH)N(CH3)2 · HCl, CAS Number: 1115-70-4, Molecular Weight: 165.62
| Sigma-Aldrich BP227 Metformin hydochloride British Pharmacopoeia (BP) Reference Standard 100 mg |
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Synonym(s): 1,1-Dimethylbiguanide hydrochloride, Metformin
Linear Formula: NH2C(=NH)NHC(=NH)N(CH3)2 · HCl
CAS Number: 1115-70-4
Molecular Weight: 165.62
EC Number: 214-230-6
MDL number: MFCD00012582
NACRES: NA.24
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PROPERTIES
grade pharmaceutical primary standard
manufacturer/tradename BP
mp 223-226 °C (lit.)
format neat
storage temp. 2-8°C
SMILES string Cl[H].CN(C)C(=N)NC(N)=N
InChI 1S/C4H11N5.ClH/c1-9(2)4(7)8-3(5)6;/h1-2H3,(H5,5,6,7,8);1H
InChI key OETHQSJEHLVLGH-UHFFFAOYSA-N
DESCRIPTION
General description
This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.
Biochem/physiol
Actions Metformin is an antidiabetic agent that reduces blood glucose levels and improves insulin sensitivity. Its metabolic effects, including the inhibition of hepatic gluconeogenesis, are mediated at least in part by activation of the LKB1-AMPK (AMP-activated protein kinase) pathway. Activation of this pathway also appears to be involved in the antiproliferative and proapoptotic actions of metformin in cancer cell lines.
Packaging
Unit quantity: 100 mg. Subject to change. The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity please visit British Pharmacopoeia
Other Notes
Sales restrictions may apply.
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