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Sigma-Aldrich C2154 Sodium cholate hydrate from bovine and/or ovine bile, ≥99% CAS No.: 206986-87-0 1 kg

Stok Kodu
LB.SA.C1254-1KG
Kısa Bilgi
Synonym(s): 3α,7α,12α-Trihydroxy-5β-cholan-24-oic acid sodium salt, Cholalic acid sodium salt Empirical Formula (Hill Notation): C24H39NaO5 · xH2O CAS Number: 206986-87-0 Molecular Weight: 430.55 (anhydrous basis) Beilstein: 3582354 EC Number: 206-643-5 MDL number: MFCD00150749 UNSPSC Code: 12161900 PubChem Substance ID: 24892390 NACRES: NA.25
Ön Siparişli Ürün
Sigma-Aldrich C2154 Sodium cholate hydrate from bovine and/or ovine bile, ≥99%
Synonym(s): 3α,7α,12α-Trihydroxy-5β-cholan-24-oic acid sodium salt, Cholalic acid sodium salt
Empirical Formula (Hill Notation):
C24H39NaO5 · xH2O
CAS Number:
206986-87-0
Molecular Weight:
430.55 (anhydrous basis)
Beilstein:
3582354
EC Number:
206-643-5
MDL number:
MFCD00150749
UNSPSC Code:
12161900
PubChem Substance ID:
24892390
NACRES:
NA.25
Sigma-Aldrich C2154 Sodium cholate hydrate from bovine and/or ovine bile, ≥99% CAS No.: 206986-87-0     
PROPERTIES
biological source bovine and/or ovine bile
Quality Level
200
description
anionic
Assay ≥99%
form
powder
mol wt
micellar avg mol wt 900-1300
aggregation number
2-3
technique(s)
DNA purification: suitable
RNA purification: suitable
western blot: suitable
CMC
9-15 mM (20-25°C)
solubility
water: 100 mg/mL, clear, colorless to light yellow
HLB 18
SMILES string
O.[Na+].C[C@H](CCC([O-])=O)C1CCC2C3[C@H](O)CC4C[C@H](O)CC[C@]4(C)C3C[C@H](O)[C@]12C
InChI 1S/C24H40O5.Na.H2O/c1-13(4-7-21(28)29)16-5-6-17-22-18(12-20(27)24(16,17)3)23(2)9-8-15(25)10-14(23)11-19(22)26;;/h13-20,22,25-27H,4-12H2,1-3H3,(H,28,29);;1H2/q;+1;/p-1/t13-,14+,15-,16-,17+,18+,19-,20+,22+,23+,24-;;/m1../s1
InChI key
MUVVIYFKOVLQHL-RCVKHMDESA-M


DESCRIPTION

General description
Sodium cholate hydrate, a non-denaturing anionic detergent, plays a crucial role in biochemical research, particularly in protein solubilization and membrane permeabilization, making it essential for protein extraction and purification, especially when dealing with membrane proteins and protein complexes. Derived from cholic acid, a prevalent human bile acid, sodium cholate hydrate′s water solubility and its applications extend to investigating the effects of various substances on cell cultures, making it a versatile tool in laboratory research.
Application
Sodium cholate hydrate has been used in a study to assess the effect of phospholipid formulation and surfactants on the dermal delivery of hydrophilic drugs from elastic liposomes. [1] It has also been used in a study to investigate the elastic deformable vesicles, transfersomes, for transdermal drug delivery. [2]
Biochem/physiol Actions
Bile Salt
Features and Benefits
- Suitable for Western blotting
- Suitable for DNA and RNA purification
- High purity product for research applications
Other Notes
For additional information on our range of Biochemicals, please complete this form.
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Sigma-Aldrich C2154 Sodium cholate hydrate from bovine and/or ovine bile, ≥99% CAS No.: 206986-87-0 1 kg Synonym(s): 3α,7α,12α-Trihydroxy-5β-cholan-24-oic acid sodium salt, Cholalic acid sodium salt Empirical Formula (Hill Notation): C24H39NaO5 · xH2O CAS Number: 206986-87-0 Molecular Weight: 430.55 (anhydrous basis) Beilstein: 3582354 EC Number: 206-643-5 MDL number: MFCD00150749 UNSPSC Code: 12161900 PubChem Substance ID: 24892390 NACRES: NA.25 LB.SA.C1254-1KG
Sigma-Aldrich C2154 Sodium cholate hydrate from bovine and/or ovine bile, ≥99% CAS No.: 206986-87-0 1 kg

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