Sigma-Aldrich M0880 Ethyl methanesulfonate liquid 1 gr
Marka
Stok Kodu
LB.SA.M0880-1G
Kısa Bilgi
Synonym(s): Ethyl mesylate, Methanesulfonic acid ethyl ester Linear Formula: CH3SO3CH2CH3 CAS Number: 62-50-0 Molecular Weight: 124.16 Beilstein: 773969 EC Number: 200-536-7 MDL number: MFCD00007559 PubChem Substance ID: 24896575 NACRES: NA.25
Garanti Süresi
24 Ay
| Sigma-Aldrich M0880 Ethyl methanesulfonate liquid 1 gr |
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Synonym(s): Ethyl mesylate, Methanesulfonic acid ethyl ester
Linear Formula: CH3SO3CH2CH3
CAS Number: 62-50-0
Molecular Weight: 124.16
Beilstein: 773969
EC Number: 200-536-7
MDL number: MFCD00007559
PubChem Substance ID: 24896575
NACRES: NA.25 |
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PROPERTIES
form liquid
Quality Level 200
refractive index n20/D 1.418 (lit.)
bp 85-86 °C/10 mmHg (lit.)
density 1.206 g/mL at 20 °C
SMILES string CCOS(C)(=O)=O
InChI 1S/C3H8O3S/c1-3-6-7(2,4)5/h3H2,1-2H3
InChI key PLUBXMRUUVWRLT-UHFFFAOYSA-N
DESCRIPTION
Application
Ethyl methanesulfonate had been used for inducing mutation in mouse embryonic fibroblasts[1], yeast [2] human embryonic kidney cell lines[3] and human lymphocytes.[4]
Biochem/physiol Actions
Ethyl methanesulfonate is a DNA ethylating agent, mutagenic to plants and animals and carcinogenic in mammals. It has been used as a model alkylating agent in studies of DNA repair processes.[5] EMS induces base substitutions of guanine-cytosine (G/C) to adenine-thymine (A/T). EMS also generates point mutations and single nucleotide polymorphisms in genomes.[6] EMS is potential chemical mutagen used for inducing mutation in rice, wheat and Arabidopsis thaliana.[7] |
