Sigma-Aldrich P8014 4α-Phorbol 12,13-didecanoate solid 1 mg
Kategori
Marka
Stok Kodu
LB.SA.P8014-1MG
Kısa Bilgi
Synonym(s): 4α-Phorbol 12-13-dicaprinate, 4αPDD Empirical Formula (Hill Notation): C40H64O8 CAS Number: 27536-56-7 Molecular Weight: 672.93 Beilstein: 2514324 MDL number: MFCD00036737 PubChem Substance ID: 24898900 NACRES: NA.77
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Sigma-Aldrich P8014 4α-Phorbol 12,13-didecanoate solid 1 mg |
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Synonym(s): 4α-Phorbol 12-13-dicaprinate, 4αPDD
Empirical Formula (Hill Notation): C40H64O8
CAS Number: 27536-56-7
Molecular Weight: 672.93
Beilstein: 2514324
MDL number: MFCD00036737
PubChem Substance ID: 24898900
NACRES: NA.77
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PROPERTIES
form solid
Quality Level 100
color white
solubility
DMSO: soluble
ethanol: soluble
methanol: soluble
storage temp. −20°C
SMILES string CCCCCCCCCC(=O)O[C@@H]1[C@@H](C)[C@@]2(O)C(C=C(CO)C[C@]3(O)C2C=C(C)C3=O)C4C(C)(C)[C@]14OC(=O)CCCCCCCCC
InChI 1S/C40H64O8/c1-7-9-11-13-15-17-19-21-32(42)47-36-28(4)39(46)30(24-29(26-41)25-38(45)31(39)23-27(3)35(38)44)34-37(5,6)40(34,36)48-33(43)22-20-18-16-14-12-10-8-2/h23-24,28,30-31,34,36,41,45-46H,7-22,25-26H2,1-6H3/t28-,30+,31-,34-,36-,38+,39-,40-/m1/s1
InChI key DGOSGFYDFDYMCW-OEFRVDPMSA-N
DESCRIPTION
Application
4α-Phorbol 12,13-didecanoate has been used as a transient receptor potential vanilloid 4 (TRPV4) agonist: to study its effects on Madin-Darby canine kidney (MDCK) cells[1]
to study its effects on Ca2+ influx in mice fallopian tubal cells[2]
to study its effects on hind paw swelling in mice[3]
Packaging
1, 5, 10 mg
Biochem/physiol Actions
4α-Phorbol 12,13-didecanoate is a transient receptor potential vanilloid 4 (TRPV4) agonist. It promotes extracellular calcium influx into the cells.[4]
Caution
Photosensitive
Reconstitution
Stock solution cannot be made in aqueous media; dissolve in a water-miscible organic solvent before dilution to working concentrations in aqueous media. |