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Sigma-Aldrich PHR1380 Ivermectin Pharmaceutical Secondary Standard; Certified Reference Material 1 gr

Stok Kodu
LB.SA.PHR1380-1G
Kısa Bilgi
Synonym(s): Ivermectin, 22,23-Dihydroavermectin B1, MK-933 CAS Number: 70288-86-7 EC Number: 274-536-0 MDL number: MFCD00869511 PubChem Substance ID: 329823357 NACRES: NA.24
Sigma-Aldrich PHR1380 Ivermectin Pharmaceutical Secondary Standard; Certified Reference Material 1 gr
Synonym(s): Ivermectin, 22,23-Dihydroavermectin B1, MK-933
CAS Number: 70288-86-7
EC Number: 274-536-0
MDL number: MFCD00869511
PubChem Substance ID: 329823357
NACRES: NA.24
Sigma-Aldrich PHR1380 Ivermectin Pharmaceutical Secondary Standard; Certified Reference Material  
PROPERTIES
grade certified reference material pharmaceutical secondary standard 
Quality Level 300 
Agency
traceable to BP 864, traceable to Ph. Eur. I8000010, traceable to USP 1354309 
API family ivermectin 
CofA current certificate can be downloaded 
technique(s) HPLC: suitable, gas chromatography (GC): suitable 
application(s) pharmaceutical (small molecule) 
format neat 
storage temp. 2-8°C 
SMILES string [H][C@@]1(O[C@]2(CC[C@@H]1C)C[C@@H]3C[C@@H](C\C=C(C)\[C@@H](O[C@H]4C[C@H](OC)[C@@H](O[C@H]5C[C@H](OC)[C@@H](O)[C@H](C)O5)[C@H](C)O4)[C@@H](C)\C=C\C=C6/CO[C@]7([H])[C@H](O)C(C)=C[C@@H](C(=O)O3)[C@]67O)O2)[C@@H](C)CC
InChI 1S/C48H74O14/c1-11-25(2)43-28(5)17-18-47(62-43)23-34-20-33(61-47)16-15-27(4)42(26(3)13-12-14-32-24-55-45-40(49)29(6)19-35(46(51)58-34)48(32,45)52)59-39-22-37(54-10)44(31(8)57-39)60-38-21-36(53-9)41(50)30(7)56-38/h12-15,19,25-26,28,30-31,33-45,49-50,52H,11,16-18,20-24H2,1-10H3/b13-12+,27-15+,32-14+/t25-,26-,28-,30-,31-,33+,34-,35-,36-,37-,38-,39-,40+,41-,42-,43+,44-,45+,47+,48+/m0/s1 
InChI key AZSNMRSAGSSBNP-XPNPUAGNSA-N
 
DESCRIPTION
General description
Pharmaceutical secondary standards for application in quality control, provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards. Ivermectin is a derivative of avermectin B1 that is used against both endo- and ectoparasites in veterinary applications. It has also been indicated as a potential drug for the management of Onchocerca volvulus, identified as the cause of ′river blindness′ in humans.[1]
Application
Ivermectin may be used as a pharmaceutical reference standard for the determination of the analyte in pharmaceutical formulations and plasma samples by chromatography techniques.[2][3]
These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements.
Analysis Note
These secondary standards offer multi-traceability to the USP, EP and BP primary standards, where they are available. Other Notes
This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.
Footnote
To see an example of a Certificate of Analysis for this material enter LRAA1636 in the slot below. This is an example certificate only and may not be the lot that you receive.
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Sigma-Aldrich PHR1380 Ivermectin Pharmaceutical Secondary Standard; Certified Reference Material 1 gr
Sigma-Aldrich PHR1380 Ivermectin Pharmaceutical Secondary Standard; Certified Reference Material 1 gr Synonym(s): Ivermectin, 22,23-Dihydroavermectin B1, MK-933, CAS Number: 70288-86-7, EC Number: 274-536-0, MDL number: MFCD00869511 LB.SA.PHR1380-1G
Sigma-Aldrich PHR1380 Ivermectin Pharmaceutical Secondary Standard; Certified Reference Material 1 gr

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