Sigma-Aldrich PHR1400 Mometasone Furoate Pharmaceutical Secondary Standard; Certified Reference Material 500 mg
Marka
Stok Kodu
LB.SA.PHR1400-500MG
Kısa Bilgi
Synonym(s): Mometasone furoate, 9α,21-dichloro-11β-hydroxy-16α-methyl 3,20-dioxopregna-1,4-dien-17-yl furan-2-carboxylate, (11β,16α)-9,21-Dichloro-17-[(2-furanylcarbonyl)oxy]-11-hydroxy-16-methylpregna-1,4-diene-3,20-dione Empirical Formula (Hill Notation): C27H30Cl2O6 CAS Number: 83919-23-7 Molecular Weight: 521.43 MDL number: MFCD00866003 PubChem Substance ID: 329823374 NACRES: NA.24
| Sigma-Aldrich PHR1400 Mometasone Furoate 500 mg |
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Synonym(s): Mometasone furoate, 9α,21-dichloro-11β-hydroxy-16α-methyl 3,20-dioxopregna-1,4-dien-17-yl furan-2-carboxylate, (11β,16α)-9,21-Dichloro-17-[(2-furanylcarbonyl)oxy]-11-hydroxy-16-methylpregna-1,4-diene-3,20-dione Empirical Formula (Hill Notation): C27H30Cl2O6
CAS Number: 83919-23-7
Molecular Weight: 521.43
MDL number: MFCD00866003
PubChem Substance ID: 329823374
NACRES: NA.24
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PROPERTIES
grade
certified reference material
pharmaceutical secondary standard
Quality Level 300
Agency
traceable to BP 768
traceable to Ph. Eur. M2900000
traceable to USP 1445470
CofA current certificate can be downloaded
technique(s)
HPLC: suitable
gas chromatography (GC): suitable
application(s) pharmaceutical (small molecule)
format neat
storage temp. 2-30°C
SMILES string C[C@@H]1C[C@H]2[C@@H]3CCC4=CC(=O)C=C[C@]4(C)[C@@]3(Cl)[C@@H](O)C[C@]2(C)[C@@]1(OC(=O)c5ccco5)C(=O)CCl
InChI 1S/C27H30Cl2O6/c1-15-11-19-18-7-6-16-12-17(30)8-9-24(16,2)26(18,29)21(31)13-25(19,3)27(15,22(32)14-28)35-23(33)20-5-4-10-34-20/h4-5,8-10,12,15,18-19,21,31H,6-7,11,13-14H2,1-3H3/t15-,18+,19+,21+,24+,25+,26+,27+/m1/s1
InChI key WOFMFGQZHJDGCX-ZULDAHANSA-N
Gene Information human ... NR3C1(2908)
DESCRIPTION
General description
Mometasone Furoate is a medication with anti-inflammatory and antipruritic properties,[1] commonly used to treat mixed infections of the skin.[2] It is also used as a corticosteroid for the treatment of asthma and its mode of action involves reducing the inflammation of the airways and preventing the loss of lung functions.[3]
Application
Mometasone Furoate may be used as a secondary pharma standard for the quantification of the analyte in pharmaceutical formulations[2][3] using various chromatography techniques. These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements.
Biochem/physiol Actions
Mometasone furoate is an anti-inflammatory glucocorticoid.
Analysis Note
These secondary standards offer multi-traceability to the USP, EP and BP primary standards, where they are available. Other Notes
This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.
Footnote
To see an example of a Certificate of Analysis for this material enter LRAC3330 in the slot below. This is an example certificate only and may not be the lot that you receive. |