Sigma-Aldrich R9504 (−)-Riboflavin BioReagent, suitable for cell culture, suitable for insect cell culture, ≥98% 25 gr
Marka
Stok Kodu
LB.SA.R9504-25G
Kısa Bilgi
Synonym(s): Lactoflavin, Vitamin B2, Vitamin G Empirical Formula (Hill Notation): C17H20N4O6 CAS Number: 83-88-5 Molecular Weight: 376.36 Beilstein: 97825 EC Number: 201-507-1 MDL number: MFCD00005022 eCl@ss: 34058005 PubChem Substance ID: 24899415 NACRES: NA.75
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Sigma-Aldrich R9504 (−)-Riboflavin |
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Synonym(s): Lactoflavin, Vitamin B2, Vitamin G
Empirical Formula (Hill Notation): C17H20N4O6
CAS Number: 83-88-5
Molecular Weight: 376.36
Beilstein: 97825
EC Number: 201-507-1
MDL number: MFCD00005022
eCl@ss: 34058005
PubChem Substance ID: 24899415
NACRES: NA.75 |
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PROPERTIES
biological source Eremothecium ashbyii
Quality Level 200
product line BioReagent
Assay ≥98%
form powder
mol wt Mw 376.36 g/mol
technique(s) cell culture | insect: suitable, cell culture | mammalian: suitable
color yellow to orange
mp 290 °C (dec.) (lit.)
solubility 0.1 M NaOH: 10 mg/mL, clear, yellow to orange
storage temp. room temp
SMILES string CC1=C(C)C=C(N(C[C@H](O)[C@@H]([C@H](O)CO)O)C(C2=N3)=NC(NC2=O)=O)C3=C1
InChI 1S/C17H20N4O6/c1-7-3-9-10(4-8(7)2)21(5-11(23)14(25)12(24)6-22)15-13(18-9)16(26)20-17(27)19-15/h3-4,11-12,14,22-25H,5-6H2,1-2H3,(H,20,26,27)/t11-,12+,14-/m0/s1
InChI key AUNGANRZJHBGPY-SCRDCRAPSA-N
DESCRIPTION
General description
Riboflavin is an essential vitamin soluble in water. Milk and eggs are found to be its major sources. Riboflavin is usually bound to enzymes in all tissues. During riboflavin localization in plasma, it is bound to albumin and specific immunoglobulins.[1]
Application
(-)-Riboflavin has been used to administer intraperitoneally to experimental mice to study its protective role in stroke in middle cerebral artery occlusion. It has also been used with Krebs′ solution, to model ischemia-like conditions in vitro.[2]
Packaging
25, 100 g in glass bottle
Biochem/physiol Actions
Riboflavin serves as a precursor for the active enzyme cofactors riboflavin 5′-monophosphate (also called flavin mononucleotide or FMN) and flavin adenine dinucleotide (FAD).[1] Riboflavin deficiency in the diet results in a well-defined syndrome known as ariboflavinosis,[3] having symptoms including cheilosis, angular stomatitis, glossitis, keratitis, and seborrhoeic dermatitis. Riboflavin exhibits protective effects against tumor development and cardiovascular disease. Its deficiency often affects metabolism involving redox reactions. Riboflavin is found essential for iron absorption, gastrointestinal development, neurogenesis, corneal vascularization and corneal opacity.[1] |
