Hoşgeldiniz
Hızlı ve Güvenli Alışverişe Giriş Yapın!
Üye Değil misiniz?
Kolayca Üye Olabilirsiniz.

Sigma-Aldrich C7017 Choline chloride ≥99% 25 gr

Stok Kodu
LB.SA.C7017-25G
Kısa Bilgi
Synonym(s): (2-Hydroxyethyl)trimethylammonium chloride Linear Formula: (CH3)3N(Cl)CH2CH2OH CAS Number: 67-48-1 Molecular Weight: 139.62 Beilstein: 3563126 EC Number: 200-655-4 MDL number: MFCD00011721 PubChem Substance ID: 57654039 NACRES: NA.25
Sigma-Aldrich C7017 Choline chloride ≥99% 25 gr
Synonym(s): (2-Hydroxyethyl)trimethylammonium chloride
Linear Formula: (CH3)3N(Cl)CH2CH2OH
CAS Number: 67-48-1
Molecular Weight: 139.62
Beilstein: 3563126
EC Number: 200-655-4
MDL number: MFCD00011721
PubChem Substance ID: 57654039
NACRES: NA.25
Sigma-Aldrich C7017 Choline chloride ≥99%  
PROPERTIES
biological source synthetic 
Assay ≥99% 
form powder 
color white 
mp 302-305 °C (dec.) (lit.) 
lipid type phospholipids 
SMILES string [Cl-].C[N+](C)(C)CCO 
InChI 1S/C5H14NO.ClH/c1-6(2,3)4-5-7;/h7H,4-5H2,1-3H3;1H/q+1;/p-1 
InChI key SGMZJAMFUVOLNK-UHFFFAOYSA-M
 
DESCRIPTION
General description
Choline is a constituent of sphingomyelin and lecithin. It is a precursor of acetylcholine. Choline plays a vital role in methyl group metabolism, carcinogenesis and lipid transport. Choline deficiency is associated with fatty liver.[1] It maintains cell structural integrity and cell signalling.[2] Choline is implicated in the synthesis of phospholipids. It acts as a potent biomarker for ischemic heart disease.[3]
Application
Choline chloride has been used:
- in choline release assay[4]
- as an endogenous agonist of sigma-1 receptors (Sig-1Rs)[5]
- as a standard to analyse interrelationships between methionine and choline metabolism[6]
Biochem/physiol Actions
Choline is an essential nutrient, commonly grouped with the B complex vitamins, that plays key roles in many biological processes.
The enzymatic activities of butyrylcholinesterase (BChE) and paraoxonase 1 (PON1), two serum enzymes synthesized by the liver and related with inflammation, were decreased in a sepsis animal model injected with LPS. Choline chloride administered intravenously at 20 mg/kg body weight prevents the LPS-mediated decreases in the activities of these two enzymes.
Substrates
Choline acetyltransferase substrate
Bu ürünün fiyat bilgisi, resim, ürün açıklamalarında ve diğer konularda yetersiz gördüğünüz noktaları öneri formunu kullanarak tarafımıza iletebilirsiniz.
Görüş ve önerileriniz için teşekkür ederiz.
Sigma-Aldrich C7017 Choline chloride ≥99%
Sigma-Aldrich C7017 Choline chloride ≥99% 25 gr Synonym(s): (2-Hydroxyethyl)trimethylammonium chloride, Linear Formula: (CH3)3N(Cl)CH2CH2OH, CAS Number: 67-48-1, Molecular Weight: 139.62, Beilstein: 3563126 LB.SA.C7017-25G
Sigma-Aldrich C7017 Choline chloride ≥99% 25 gr

Tavsiye Et

*
*
*
IdeaSoft® | E-Ticaret paketleri ile hazırlanmıştır.