Sigma-Aldrich PHR1161 Procaine hydrochloride Pharmaceutical Secondary Standard; Certified Reference Material 1 gr
Kategori
Marka
Stok Kodu
LB.SA.PHR1161-G
Kısa Bilgi
Synonym(s): 4-Aminobenzoic acid 2-diethylaminoethyl ester, p-Aminobenzoic acid diethylaminoethyl ester hydrochloride, Novocaine hydrochloride Linear Formula: H2NC6H4CO2CH2CH2N(C2H5)2·HCl CAS Number: 51-05-8 Molecular Weight: 272.77 Beilstein: 3917802 EC Number: 200-077-2 MDL number: MFCD00013000 PubChem Substance ID: 329823178 NACRES: NA.24
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Sigma-Aldrich PHR1161 Procaine hydrochloride 1 gr |
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Synonym(s): 4-Aminobenzoic acid 2-diethylaminoethyl ester, p-Aminobenzoic acid diethylaminoethyl ester hydrochloride, Novocaine hydrochloride
Linear Formula: H2NC6H4CO2CH2CH2N(C2H5)2·HCl
CAS Number: 51-05-8
Molecular Weight: 272.77
Beilstein: 3917802
EC Number: 200-077-2
MDL number: MFCD00013000
PubChem Substance ID: 329823178
NACRES: NA.24 |
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PROPERTIES
grade certified reference material, pharmaceutical secondary standard
Quality Level 300
Agency traceable to USP 1564006
API family procaine
CofA current certificate can be downloaded
technique(s) HPLC: suitable, gas chromatography (GC): suitable
mp 155-156 °C (lit.)
application(s) pharmaceutical (small molecule)
format neat
storage temp. 2-30°C
SMILES string Cl.CCN(CC)CCOC(=O)c1ccc(N)cc1 InChI 1S/C13H20N2O2.ClH/c1-3-15(4-2)9-10-17-13(16)11-5-7-12(14)8-6-11;/h5-8H,3-4,9-10,14H2,1-2H3;1H
InChI key HCBIBCJNVBAKAB-UHFFFAOYSA-N
Gene Information human ... SCN10A(6336) , SCN11A(11280) , SCN1A(6323) , SCN2A(6326) , SCN3A(6328) , SCN4A(6329) , SCN5A(6331) , SCN7A(6332) , SCN8A(6334) , SCN9A(6335)
DESCRIPTION
General description
Procaine hydrochloride is a synthetic compound that belongs to the class of local anesthetic drugs. It has a structure similar to the natural compounds that participate in nerve impulse transmission. It shows interaction with the cellular membranes causing membrane lipids to expand, membrane-bound calcium to displace and change the structure of the proteins that are responsible for regulating the cell permeability and shape.[1][2][3] Pharmaceutical secondary standards for application in quality control, provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards.
Application
Procaine hydrochloride can be used as a pharmaceutical reference standard for the determination of the analyte in pharmaceutical formulations by electrochemical,[4] chemiluminescence,[5] and spectrophotometric techniques.[6][7][8]
These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements.
Analysis Note
These secondary standards offer multi-traceability to the USP, EP (PhEur) and BP primary standards, where they are available.
Other Notes
This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis. Values of analytes vary lot to lot.
Footnote
To see an example of a Certificate of Analysis for this material enter LRAA7177 in the slot below. This is an example certificate only and may not be the lot that you receive. |
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