Sigma-Aldrich PHR1537 Oxytetracycline Pharmaceutical Secondary Standard; Certified Reference Material 1 gr
Kategori
Marka
Stok Kodu
LB.SA.PHR1537-1G
Kısa Bilgi
Synonym(s): Oxytetracycline dihydrate, OTC Empirical Formula (Hill Notation): C22H24N2O9 · 2H2O CAS Number: 6153-64-6 Molecular Weight: 496.46 EC Number: 201-212-8 MDL number: MFCD00151234 PubChem Substance ID: 329823449 NACRES: NA.24
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Sigma-Aldrich PHR1537 Oxytetracycline 1 gr |
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Synonym(s): Oxytetracycline dihydrate, OTC
Empirical Formula (Hill Notation): C22H24N2O9 · 2H2O
CAS Number: 6153-64-6
Molecular Weight: 496.46
EC Number: 201-212-8
MDL number: MFCD00151234
PubChem Substance ID: 329823449
NACRES: NA.24 |
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PROPERTIES
grade certified reference material, pharmaceutical secondary standard
Quality Level 300
Agency traceable to BP 782, traceable to Ph. Eur. Y0001896, traceable to USP 1491004
API family oxytetracycline
CofA current certificate can be downloaded
packaging pkg of 1 g
technique(s) HPLC: suitable, gas chromatography (GC): suitable
application(s) pharmaceutical (small molecule)
format neat
storage temp. -10 to -25°C
SMILES string O.[H][C@@]12[C@@H](O)[C@@]3([H])C(C(=O)c4c(O)cccc4[C@@]3(C)O)=C(O)[C@]1(O)C(=O)C(C(N)=O)=C(O)[C@H]2N(C)C
InChI 1S/C22H24N2O9.H2O/c1-21(32)7-5-4-6-8(25)9(7)15(26)10-12(21)17(28)13-14(24(2)3)16(27)11(20(23)31)19(30)22(13,33)18(10)29;/h4-6,12-14,17,25,27-29,32-33H,1-3H3,(H2,23,31);1H2/t12-,13-,14+,17+,21-,22+;/m1./s1
InChI key IBZHEBHGZFICKS-IFLJXUKPSA-N
DESCRIPTION
General description
Pharmaceutical secondary standards for application in quality control, provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards. Oxytetracycline is a broad-spectrum antibiotic which finds a wide use in veterinary medicine because of its potential to inhibit the protein synthesis in gram-positive and gram-negative bacteria. It can be used on animal species like cattle, sheep, goats and pigs.[1]
Application
Oxytetracycline may be used as a pharmaceutical reference standard for the determination of the analyte in pharmaceutical formulations by chromatography[1][2] and spectrofluorimetry[3] techniques. These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements. Biochem/physiol Actions Antibiotic produced by Streptomyces rimosus. Mode of Action: Inhibits protein synthesis (elongation) by preventing binding of aminoacyl-tRNA to the 30S subunit. Antimicrobial spectrum: Gram-negative and Gram-positive bacteria. Mode of Resistance: Active efflux, ribosome protection, tetracycline inactivation.
Analysis Note
These secondary standards offer multi-traceability to the USP, EP and BP primary standards, where they are available.
Other Notes
This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.
Footnote
To see an example of a Certificate of Analysis for this material enter LRAC0364 in the slot below. This is an example certificate only and may not be the lot that you receive. |
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